Villarreal vs. Manchester City Prediction: Today's Champions League Expert Picks & Best Bets
 
        
    Last Updated: October 21, 2025 1:51 PM EDT • 2 minute read X Social Google News Link
 
                                Just a couple of hours now until Champions League gets underway again, and my Villarreal vs. Manchester City prediction digs into why the visitors to Estadi de la Ceramica in Villarreal, Spain, should come away with the win. The action kicks off at 3 p.m. ET (Paramount+).
Manchester City is the -138 road betting favorite, but my Champions League predictions are more focused on the total. I'm also targeting a Manchester City playmaker who should deliver a strong performance.
⚽ Villarreal vs. Manchester City predictions
Soccer picks for Tuesday; odds subject to change.
- Game pick: Manchester City ML (-138 via bet365) ⭐⭐⭐⭐
- Over/Under pick: Over 2.5 (-160 via Caesars) ⭐⭐⭐⭐
- Player prop pick: Tijjani Reijnders assist (+390 via DraftKings) ⭐⭐⭐
✅ Villarreal vs. Manchester City best bet
⬆️ Over 2.5 total goals (-160) ⭐⭐⭐⭐
With both teams sporting impressive attacking records heading into Tuesday’s contest, I’m backing the total to go Over 2.5 goals.
Villarreal have 10 goals in their last six games, so expect them to create opportunities to score at home, where they last held Juventus to a 2-2 draw in the Champions League. However, it’s also going to be a busy day for Villarreal’s defense again.
Manchester City will see plenty of the ball, which should lead to opportunities for one of Europe’s most potent attacks to terrorize Villarreal’s shaky defense. Manchester City, winners of six of their last eight games, are averaging over two goals a game and have 23 goals in all competitions this season.
A $10 bet at Caesars on both teams scoring will net a profit of $6.20
💰 Best Villarreal vs. Manchester City player prop bet
Our player prop odds tool shows the best odds for every market across legal sportsbooks in your area.
🔥 Tijjani Reijnders assist (+390) ⭐⭐⭐
With Erling Haaland playing some of the best soccer of his career, it might be wise to bet on a Manchester City playmaker getting an assist. Tijjani Reijnders could be a decent bet to register a helper for the Norwegian forward who features in our Matchday 3 predictions & best bets.
The Dutch midfielder, who arrived at City from AC Milan last summer, has three assists in all competitions, with two of those assists helping Haaland score.
Jeremy Doku is another good candidate to get an assist, but I’m backing Reijnders' vision and passing skills to aid in Manchester City’s scoring efforts against what should be a difficult Villarreal team. A $10 bet on Reijnders getting an assist at DraftKings will net a profit of $39.
📊 Villarreal vs. Manchester City odds
Champions League odds updated live in real time.
📺 How to watch Villarreal vs. Manchester City
- Date: Tuesday, Oct. 21
- Kickoff: 3 p.m. ET
- Where: Estadi de la Ceramica
- TV: Paramount+
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        Gordon Brunt
 
                     
                     
                     
                     
                    